Nux Vomica: Keynotes, Mind and Clinical Picture
Nux vomica from Boericke, Kent and Allen: the irritable, oversensitive and zealous type, ill effects of stimulants and sedentary strain, chilliness, 3 a.m. waking, ineffectual urging, modalities, particulars and differentials with Pulsatilla, Bryonia, Ignatia and Staphysagria.
Dr. Parag Sharma
B.H.M.S., M.D., P.hD (Hom.)
- 18 Oct 2026
- 9 min read

On this page
- What is Nux vomica?
- What are the keynotes of Nux vomica?
- What is the Nux vomica mind picture?
- What are the generals, thermal state and cravings?
- What are the modalities of Nux vomica?
- What are the key particulars of Nux vomica by region?
- What are its relationships and differentials?
- How does HomeoNetix help with Nux vomica and its differentials?
In short
Nux vomica's classical keynotes are an irritable, impatient, oversensitive and zealous patient; ill effects of coffee, alcohol, rich food, mental strain and sedentary habits; marked chilliness and aversion to uncovering; waking at 3 or 4 a.m.; and spasmodic digestive complaints with frequent, ineffectual urging to stool. Boericke calls it the greatest of polychrests.
- Boericke: the greatest of polychrests, often the first remedy after much dosing, if the symptoms correspond.
- The type is thin, quick, zealous and irritable, oversensitive to noise, odours, light and contradiction.
- Chilly: cannot uncover without chilliness, even when the body is burning hot in fever.
- Ineffectual urging is central; Boericke says absence of all desire for stool counts against Nux.
- Better in damp, wet weather, from a finished nap, in the evening at rest, and from strong pressure.
Nux vomica is indicated when the symptom picture shows an irritable, impatient, oversensitive and zealous patient, a sedentary life of mental strain with stimulants and rich food, chilliness with an aversion to being uncovered, and spasmodic digestive complaints with frequent ineffectual urging. Boericke calls it "the greatest of polychrests" because so many of its symptoms match the commonest complaints.
This guide sets out the classical Materia Medica of Nux vomica from Boericke, Kent and Allen, with relationships and differentials.
What is Nux vomica?
Nux vomica is the poison nut, the seed of Strychnos nux-vomica, a tree native to India and South-east Asia. The seeds are intensely bitter and are a major source of the poisonous alkaloids strychnine and brucine. Allen places it in the Loganiaceae, the same family he gives for Ignatia.
Boericke describes Nux as "frequently the first remedy, indicated after much dosing, establishing a sort of equilibrium of forces." Allen agrees: one of the best remedies with which to begin a case that has been drugged by mixtures and "hot medicines," but only if the symptoms correspond. Kent explains the clinical reason: over-drugged patients are so oversensitive that it can be impossible to get reliable symptoms until they settle.
What are the keynotes of Nux vomica?
The type. Boericke: "rather thin, spare, quick, active, nervous, and irritable"; does much mental work under strain and leads a sedentary life. Allen: "thin, irritable, careful, zealous persons."
Oversensitive to everything. Noise, odours, light, music; "trifling ailments are unbearable"; "every harmless word offends" (Allen).
Ill effects of a way of living. Allen lists coffee, tobacco, alcohol, highly spiced food, overeating, long mental exertion, sedentary habits and loss of sleep.
Chilliness. Chilly on the least movement and from being uncovered; must be covered in every stage of fever (Allen).
Spasmodic, ineffectual action. Boericke: "Nux always seems to be out of tune; inharmonious spasmodic action." Frequent, ineffectual urging to stool; wants to vomit but cannot.
The sleep pattern. Allen: falls asleep in the evening hours before bedtime, wakes at 3 or 4 a.m., then falls into a dreamy sleep at daybreak and wakes tired.
What is the Nux vomica mind picture?
Boericke's mind section: "Very irritable: sensitive to all impressions. Ugly, malicious. Cannot bear noises, odors, light." Does not want to be touched; time passes too slowly; disposed to reproach others; "sullen, fault-finding."
Allen quotes Hahnemann's own description: "Nux is chiefly successful with persons of an ardent character; of an irritable, impatient temperament, disposed to anger, spite or deception." He adds persons "who are very particular, careful, but inclined to become easily excited or angered."
Kent gives the scene every practitioner recognises. A business man has been at his desk until he is tired out, has "a great many irons in the fire," lies awake with the affairs of the day crowding on him, and finally "brain fag comes on." When the details come at him he gets angry. Kent stresses that this irritability "is a weakness and is accompanied by physical weakness."
What are the generals, thermal state and cravings?
Thermal state. Nux is chilly. Boericke: "Nux patients are easily chilled, avoid open air." In fever the body may be burning hot, yet the patient "cannot move or uncover without feeling chilly." Allen describes a repugnance to cold air.
Desires and aversions. Kent: "craves stimulants, pungent, bitter, succulent things, something to brace him up," and is aggravated by meat. Boericke: desire for stimulants; "loves fats and tolerates them well," noting this as the opposite of Pulsatilla.
Digestion. Allen: pressure in the stomach "an hour or two after eating as from a stone"; must loosen the clothing; "cannot use the mind for two or three hours after a meal"; sleepy after dinner. Nausea in the morning, with the wish "If I could only vomit I would be so much better."
Sleep. Boericke: cannot sleep after 3 a.m. until towards morning; wakes feeling wretched; better after a short sleep unless aroused.
What are the modalities of Nux vomica?
Worse | Better |
|---|---|
Morning; waking at 3 to 4 a.m. | A nap, if allowed to finish it |
Mental exertion | Evening, while at rest |
After eating or overeating | Damp, wet weather |
Touch, noise, anger | Strong pressure |
Spices, stimulants, narcotics | Lying down (Allen) |
Dry weather; cold air |
|
Note the inversion with many remedies: Nux is better in damp, wet weather. Record that modality against each complaint as part of the complete symptom; when it repeats across the case it becomes a strong general.
What are the key particulars of Nux vomica by region?
Head: headache in the occiput or over the eyes, with vertigo; intoxicated feeling, worse in the morning, from mental exertion, tobacco, alcohol and coffee; pressing on the vertex "as if a nail driven in."
Nose: coryza fluent by day, stuffed at night and outdoors; stuffy colds after dry, cold air.
Stomach: sour taste and nausea in the morning; weight like a stone some hours after eating; difficult belching.
Stool: constipation with frequent, ineffectual urging, "feeling as if part remained unexpelled." Boericke adds that "absence of all desire for defecation is a contra-indication."
Urine: irritable bladder; frequent calls, little and often.
Back: backache in the lumbar region; "must sit up in order to turn in bed."
Extremities: cramps in the calves and soles; sudden loss of power of the arms and legs in the morning.
Fever: cold stage predominates; chilly, must be covered in every stage.
What are its relationships and differentials?
Relationships. Boericke lists Sulphur and Sepia as complementary, Zinc as inimical, and Coffea, Ignatia and Cocculus as antidotes. Allen calls Sulphur complementary "in nearly all diseases," says Nux follows well after Arsenicum, Ipecacuanha, Phosphorus, Sepia and Sulphur, and is followed well by Bryonia, Pulsatilla and Sulphur.
Differentials.
Remedy | Point of difference (classical sources) |
|---|---|
Pulsatilla | Allen: the sleep is the reverse (wide awake in the evening, sound asleep at rising time); Boericke: Pulsatilla is averse to fat where Nux tolerates it; Pulsatilla is mild where Nux is fiery (see our Pulsatilla guide) |
Bryonia | Allen: constipation with no desire for stool, where Nux has frequent ineffectual urging; Bryonia is worse from any motion |
Ignatia | Allen: also offended by a harmless word, but the remedy of grief and of great contradictions, with sighing |
Staphysagria | Allen: insulted, he subdues his wrath and goes home sick; Allen marks this as "the rev. of Nux," which flares outward |
A short study case
A bank manager in his forties, de-identified, eats late, drinks several cups of coffee to stay sharp and wakes at 3 a.m. thinking about work. After meals he feels a weight in the stomach and must loosen his belt. He has frequent urging to stool with little result, snaps at noise and at his children, and sits in the consulting room with his jacket on. Each line is a Nux vomica line in Boericke, Kent or Allen. The concomitants and the time modalities would then be compared against Bryonia and Lycopodium (see our Lycopodium guide).
How does HomeoNetix help with Nux vomica and its differentials?
HomeoNetix keeps Kent, Knerr, Boger and Boericke repertories and 19 classical Materia Medica titles, including Boericke, Allen, Kent's Lectures and Hahnemann, inside the patient's case, with AI case analysis that explains its classical reasoning while the doctor decides. You can try it with a free guided demo.
This article is for practitioners and students. It is not medical advice for patients.
Frequently asked questions
What type of person is Nux vomica suited to?
Boericke describes the typical Nux patient as rather thin, spare, quick, active, nervous and irritable, doing much mental work under strain with a sedentary life. Allen describes thin, irritable, careful, zealous persons, and quotes Hahnemann on persons of an ardent character and impatient temperament. The type is a guide, but the prescription still rests on the symptoms.
What is the sleep pattern of Nux vomica?
Allen describes a patient who cannot keep from falling asleep in the evening hours before bedtime, wakes at 3 or 4 a.m., then falls into a dreamy sleep at daybreak and wakes tired and weak. Boericke adds that he is better after a short sleep unless aroused. Allen notes this is the reverse of Pulsatilla.
How is Nux vomica different from Bryonia in constipation?
Allen describes Nux constipation as frequent unsuccessful desire, passing small quantities, with a sensation as if not finished. He contrasts this with Bryonia, Opium and Sulphur, which have inactive bowels with no desire. Boericke goes further and says that absence of all desire for defecation is a contra-indication for Nux vomica.
Is Nux vomica hot or chilly?
Nux vomica is chilly. Boericke says Nux patients are easily chilled and avoid open air, and that in fever the body may be burning hot while the patient cannot move or uncover without feeling chilly. Allen says the patient must be covered in every stage of fever. Its nasal catarrh is the exception: worse in a warm room.
What are the complementary remedies and antidotes of Nux vomica?
Boericke lists Sulphur and Sepia as complementary, Zinc as inimical, and Coffea, Ignatia and Cocculus as antidotes. Allen calls Sulphur complementary in nearly all diseases, says Nux follows well after Arsenicum, Ipecacuanha, Phosphorus, Sepia and Sulphur, and is followed well by Bryonia, Pulsatilla and Sulphur.
Sources
- 1.Boericke, Pocket Manual of Homoeopathic Materia Medica, 8th ed. (1922), Internet Archivearchive.org
- 2.Kent, Lectures on Homoeopathic Materia Medica (1904), Internet Archivearchive.org
- 3.H. C. Allen, Keynotes and Characteristics (1899), Internet Archivearchive.org
- 4.Strychnos nux-vomica, Wikipediaen.wikipedia.org
Written by
Dr. Parag Sharma
B.H.M.S., M.D., P.hD (Hom.)


